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Also, the conolidine molecule did not interact with the classical receptors, this means that it wouldn't compete in opposition to opioid peptides to bind to these receptors.The second soreness phase is because of an inflammatory response, while the principal response is acute damage for the nerve fibers. Conolidine injection was observed to suppres

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In the screening exam involving much more than 240 receptors, the researchers discovered that conolidine demonstrated binding on the ACKR3 receptor in equally human beings and mice, blocking ACKR3 from binding to opioid peptides.Scientists think that blocking this scavenger receptor ensures that it could no more protect against Normally produced op

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